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Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure

FSGS is the most common primary glomerular disease underlying ESRD in the United States and is increasing in incidence globally. FSGS results from podocyte injury, yet the mechanistic details of disease pathogenesis remain unclear. This has resulted in an unmet clinical need for cell-specific therap...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Schwartzman, Monica, Reginensi, Antoine, Wong, Jenny S., Basgen, John M., Meliambro, Kristin, Nicholas, Susanne B., D'Agati, Vivette, McNeill, Helen, Campbell, Kirk N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696566/
https://ncbi.nlm.nih.gov/pubmed/26015453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090916
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