Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure

FSGS is the most common primary glomerular disease underlying ESRD in the United States and is increasing in incidence globally. FSGS results from podocyte injury, yet the mechanistic details of disease pathogenesis remain unclear. This has resulted in an unmet clinical need for cell-specific therap...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Schwartzman, Monica, Reginensi, Antoine, Wong, Jenny S., Basgen, John M., Meliambro, Kristin, Nicholas, Susanne B., D'Agati, Vivette, McNeill, Helen, Campbell, Kirk N.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696566/
https://ncbi.nlm.nih.gov/pubmed/26015453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090916
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