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Genome-Wide Fitness and Genetic Interactions Determined by Tn-seq, a High-Throughput Massively Parallel Sequencing Method for Microorganisms

The lagging annotation of bacterial genomes and the inherent genetic complexity of many phenotypes is hindering the discovery of new drug targets and the development of new antimicrobial agents and vaccines. This unit presents Tn-seq, a method that has made it possible to quantitatively determine fi...

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Bibliografiske detaljer
Udgivet i:Curr Protoc Microbiol
Main Authors: van Opijnen, Tim, Lazinski, David W., Camilli, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696536/
https://ncbi.nlm.nih.gov/pubmed/25641100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780471729259.mc01e03s36
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