A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration

Fascin is an actin-binding and bundling protein that is highly upregulated in most epithelial cancers. Fascin promotes cell migration and adhesion dynamics in vitro and tumour cell metastasis in vivo. However, potential non-actin bundling roles for fascin remain unknown. Here, we show for the first...

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Publicat a:J Cell Sci
Autors principals: Villari, Giulia, Jayo, Asier, Zanet, Jennifer, Fitch, Briana, Serrels, Bryan, Frame, Margaret, Stramer, Brian M., Goult, Benjamin T., Parsons, Maddy
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696496/
https://ncbi.nlm.nih.gov/pubmed/26542021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175760
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