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A direct interaction between fascin and microtubules contributes to adhesion dynamics and cell migration
Fascin is an actin-binding and bundling protein that is highly upregulated in most epithelial cancers. Fascin promotes cell migration and adhesion dynamics in vitro and tumour cell metastasis in vivo. However, potential non-actin bundling roles for fascin remain unknown. Here, we show for the first...
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Publicado no: | J Cell Sci |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4696496/ https://ncbi.nlm.nih.gov/pubmed/26542021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175760 |
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