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Distribution of Gemcitabine Is Nearly Homogenous in Two Orthotopic Murine Models of Pancreatic Cancer

Pancreatic cancer is one of the leading causes of cancer-related death in the United States. Gemcitabine is a common treatment, but response rates are low, perhaps due in part to tumor hypoxia. We utilized (14)C-labeled gemcitabine to map distribution of the drug with respect to perfused and hypoxic...

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Vydáno v:Cancer Biother Radiopharm
Hlavní autoři: Kramer, Robin M., Russell, James, Humm, John L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696432/
https://ncbi.nlm.nih.gov/pubmed/26203552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2015.1869
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