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Targeting the Hedgehog Pathway in Pediatric Medulloblastoma

Medulloblastoma (MB), a primitive neuroectomal tumor of the cerebellum, is the most common malignant pediatric brain tumor. The cause of MB is largely unknown, but aberrant activation of Hedgehog (Hh) pathway is responsible for ~30% of MB. Despite aggressive treatment with surgical resection, radiat...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Huang, Sherri Y., Yang, Jer-Yen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695880/
https://ncbi.nlm.nih.gov/pubmed/26512695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7040880
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