Translational control of nociception via 4E-binding protein 1

Activation of the mechanistic/mammalian target of rapamycin (mTOR) kinase in models of acute and chronic pain is strongly implicated in mediating enhanced translation and hyperalgesia. However, the molecular mechanisms by which mTOR regulates nociception remain unclear. Here we show that deletion of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Khoutorsky, Arkady, Bonin, Robert P, Sorge, Robert E, Gkogkas, Christos G, Pawlowski, Sophie Anne, Jafarnejad, Seyed Mehdi, Pitcher, Mark H, Alain, Tommy, Perez-Sanchez, Jimena, Salter, Eric W, Martin, Loren, Ribeiro-da-Silva, Alfredo, De Koninck, Yves, Cervero, Fernando, Mogil, Jeffrey S, Sonenberg, Nahum
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Biochemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695384/
https://ncbi.nlm.nih.gov/pubmed/26678009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12002
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker