Translational control of nociception via 4E-binding protein 1

Activation of the mechanistic/mammalian target of rapamycin (mTOR) kinase in models of acute and chronic pain is strongly implicated in mediating enhanced translation and hyperalgesia. However, the molecular mechanisms by which mTOR regulates nociception remain unclear. Here we show that deletion of...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Khoutorsky, Arkady, Bonin, Robert P, Sorge, Robert E, Gkogkas, Christos G, Pawlowski, Sophie Anne, Jafarnejad, Seyed Mehdi, Pitcher, Mark H, Alain, Tommy, Perez-Sanchez, Jimena, Salter, Eric W, Martin, Loren, Ribeiro-da-Silva, Alfredo, De Koninck, Yves, Cervero, Fernando, Mogil, Jeffrey S, Sonenberg, Nahum
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
Onderwerpen:
Biochemistry
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695384/
https://ncbi.nlm.nih.gov/pubmed/26678009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12002
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items