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Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement
Chromosome rearrangement plays a causal role in tumorigenesis by contributing to the inactivation of tumor suppressor genes, the dysregulated expression or amplification of oncogenes and the generation of novel gene fusions. Chromosome breaks are important intermediates in this process. How, when an...
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| Publicado en: | Trends Cancer |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695301/ https://ncbi.nlm.nih.gov/pubmed/26726318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2015.10.007 |
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