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Genomic Rearrangements in Prostate Cancer

PURPOSE OF REVIEW: Genomic instability is a fundamental feature of human cancer, leading to the activation of oncogenes and inactivation of tumor suppressors. In prostate cancer, structural genomic rearrangements, resulting in gene fusions, amplifications and deletions, are a critical mechanism effe...

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Detalhes bibliográficos
Publicado no:Curr Opin Urol
Main Authors: Barbieri, Christopher E., Rubin, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269103/
https://ncbi.nlm.nih.gov/pubmed/25393273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOU.0000000000000129
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