Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF

The growth factors derived from the microenvironment create an environment conducive to tumor growth and survival. HGF deprivation using neutralizing antibody enhanced chemosensitivity in colorectal cancer cells (CRC). We determined secreted HGF in fibroblast conditioned medium (CM). Combination tre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Woo, Jong Kyu, Kang, Ju-Hee, Kim, BoRa, Park, Byung Hee, Shin, Kum-Joo, Song, Seong-Won, Kim, Jung Ju, Kim, Hwan-Mook, Lee, Sang-Jin, Oh, Seung Hyun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695169/
https://ncbi.nlm.nih.gov/pubmed/26090722
Tagiau: Ychwanegu Tag
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