Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF

The growth factors derived from the microenvironment create an environment conducive to tumor growth and survival. HGF deprivation using neutralizing antibody enhanced chemosensitivity in colorectal cancer cells (CRC). We determined secreted HGF in fibroblast conditioned medium (CM). Combination tre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Woo, Jong Kyu, Kang, Ju-Hee, Kim, BoRa, Park, Byung Hee, Shin, Kum-Joo, Song, Seong-Won, Kim, Jung Ju, Kim, Hwan-Mook, Lee, Sang-Jin, Oh, Seung Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695169/
https://ncbi.nlm.nih.gov/pubmed/26090722
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