pHLIP-mediated targeting of truncated tissue factor to tumor vessels causes vascular occlusion and impairs tumor growth

Occluding tumor blood supply by delivering the extracellular domain of coagulation-inducing protein tissue factor (truncated tissue factor, tTF) to tumor vasculature has enormous potential to eliminate solid tumors. Yet few of the delivery technologies are moved into clinical practice due to their n...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Suping, Tian, Yanhua, Zhao, Ying, Zhang, Yinlong, Su, Shishuai, Wang, Jing, Wu, Meiyu, Shi, Quanwei, Anderson, Gregory J., Thomsen, Johannes, Zhao, Ruifang, Ji, Tianjiao, Wang, Jie, Nie, Guangjun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695134/
https://ncbi.nlm.nih.gov/pubmed/26143637
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