RICTOR involvement in the PI3K/AKT pathway regulation in melanocytes and melanoma

Several studies have highlighted the importance of the PI3K pathway in melanocytes and its frequent over-activation in melanoma. However, little is known about regulation of the PI3K pathway in melanocytic cells. We showed that normal human melanocytes are less sensitive to selective PI3K or mTOR in...

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Vydáno v:Oncotarget
Hlavní autoři: Laugier, Florence, Finet-Benyair, Adeline, André, Jocelyne, Rachakonda, P. Sivaramakrishna, Kumar, Rajiv, Bensussan, Armand, Dumaz, Nicolas
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695048/
https://ncbi.nlm.nih.gov/pubmed/26356562
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