RICTOR involvement in the PI3K/AKT pathway regulation in melanocytes and melanoma

Several studies have highlighted the importance of the PI3K pathway in melanocytes and its frequent over-activation in melanoma. However, little is known about regulation of the PI3K pathway in melanocytic cells. We showed that normal human melanocytes are less sensitive to selective PI3K or mTOR in...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Laugier, Florence, Finet-Benyair, Adeline, André, Jocelyne, Rachakonda, P. Sivaramakrishna, Kumar, Rajiv, Bensussan, Armand, Dumaz, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695048/
https://ncbi.nlm.nih.gov/pubmed/26356562
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