A genome-wide assessment of rare copy number variants in colorectal cancer

Colorectal cancer (CRC) is a complex disease with an estimated heritability of approximately 35%. However, known CRC-related common single nucleotide polymorphisms (SNPs) can only explain ~0.65% of the heritability. This “missing heritability” may be explained partially by rare copy number variants...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Zhenli, Yu, Dan, Gan, Meifu, Shan, Qiaonan, Yin, Xiaoyang, Tang, Shunli, Zhang, Shuai, Shi, Yongyong, Zhu, Yimin, Lai, Maode, Zhang, Dandan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694911/
https://ncbi.nlm.nih.gov/pubmed/26315111
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