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Polymorphisms involving gain or loss of CpG sites are significantly enriched in trait-associated SNPs

Some single nucleotide polymorphisms (SNPs) influence the existence of CpG sites, the basis of DNA modification such as methylation and hydroxymethylation. These polymorphisms can lead to gain or loss of CpG sites and were defined as CpG site related SNPs (cgSNPs) in this study. The cgSNPs change DN...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Dan, Li, Zhenli, Yu, Dan, Wan, Ledong, Zhu, Yimin, Lai, Maode, Zhang, Dandan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741875/
https://ncbi.nlm.nih.gov/pubmed/26503467
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