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Copy number increase of HER-2 in colorectal cancers

HER-2 is involved in genetic instability and is overexpressed in a number of human carcinomas, including colorectal cancer (CRC). The choromosomal locus of HER-2, 17q21, is frequently amplified in breast cancer, but the correlation between copy-number variations and HER-2 overexpression in CRC has y...

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Main Authors: XIONG, YI, FANG, ZHENGYU, ZHANG, CHAO, QI, GUOLONG, LIU, WENLI, ZHANG, WEI, WAN, JUN
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410603/
https://ncbi.nlm.nih.gov/pubmed/22866086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2010.225
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