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Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow

Selectin-mediated tumor cell tethering to host cells, such as vascular endothelial cells, is a critical step in the process of cancer metastasis. We recently identified sialofucosylated mucin16 (MUC16) and podocalyxin (PODXL) as the major functional E- and L-selectin ligands expressed on the surface...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Shea, Daniel J., Wirtz, Denis, Stebe, Kathleen J., Konstantopoulos, Konstantinos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694797/
https://ncbi.nlm.nih.gov/pubmed/26329844
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