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Distinct Kinetic and Molecular Requirements Govern CD44 Binding to Hyaluronan versus Fibrin(ogen)

CD44 is a multifunctional glycoprotein that binds to hyaluronan and fibrin(ogen). Alternative splicing is responsible for the generation of numerous different isoforms, the smallest of which is CD44s. Insertion of variant exons into the extracellular membrane proximal region generates the variant is...

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Bibliografiske detaljer
Main Authors: Raman, Phrabha S., Alves, Christina S., Wirtz, Denis, Konstantopoulos, Konstantinos
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414901/
https://ncbi.nlm.nih.gov/pubmed/22947857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.039
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