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Distinct Kinetic and Molecular Requirements Govern CD44 Binding to Hyaluronan versus Fibrin(ogen)

CD44 is a multifunctional glycoprotein that binds to hyaluronan and fibrin(ogen). Alternative splicing is responsible for the generation of numerous different isoforms, the smallest of which is CD44s. Insertion of variant exons into the extracellular membrane proximal region generates the variant is...

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Detalhes bibliográficos
Main Authors: Raman, Phrabha S., Alves, Christina S., Wirtz, Denis, Konstantopoulos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414901/
https://ncbi.nlm.nih.gov/pubmed/22947857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.039
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