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Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
RNA interference (RNAi) is a conserved sequence-specific gene regulatory mechanism(1–3) mediated by the RNA-induced silencing complex (RISC), which is composed of a single-stranded guide RNA and an Argonaute protein. The PIWI domain, a highly conserved motif within Argonaute, has been shown to adopt...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694588/ https://ncbi.nlm.nih.gov/pubmed/15800629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03514 |
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