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A Potential Protein-RNA Recognition Event along the RISC-Loading Pathway from the Structure of A. aeolicus Argonaute with Externally Bound siRNA

Argonaute proteins are key components of the RNA-induced silencing complex (RISC). They provide both architectural and catalytic functionalities associated with small interfering RNA (siRNA) guide strand recognition and subsequent guide strand-mediated cleavage of complementary mRNAs. We report on t...

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Bibliographische Detailangaben
Veröffentlicht in:Structure
Hauptverfasser: Yuan, Yu-Ren, Pei, Yi, Chen, Hong-Ying, Tuschl, Thomas, Patel, Dinshaw J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692372/
https://ncbi.nlm.nih.gov/pubmed/17027504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.08.009
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