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The survivin suppressant YM155 reverses doxorubicin resistance in osteosarcoma

Doxorubicin (DOX) is one of the widely used chemotherapeutic drugs for the treatment of human osteosarcoma (OS). However, acquisition of DOX resistance is common in patients with OS, leading to local and distant failure. In this study, we demonstrate that survivin expression is significantly upregul...

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Bibliografische gegevens
Gepubliceerd in:Int J Clin Exp Med
Hoofdauteurs: Zhang, Zhuo, Zhang, Yunfeng, Lv, Jiayin, Wang, Jincheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694298/
https://ncbi.nlm.nih.gov/pubmed/26770398
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