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The survivin suppressant YM155 reverses doxorubicin resistance in osteosarcoma

Doxorubicin (DOX) is one of the widely used chemotherapeutic drugs for the treatment of human osteosarcoma (OS). However, acquisition of DOX resistance is common in patients with OS, leading to local and distant failure. In this study, we demonstrate that survivin expression is significantly upregul...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Exp Med
Hauptverfasser: Zhang, Zhuo, Zhang, Yunfeng, Lv, Jiayin, Wang, Jincheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694298/
https://ncbi.nlm.nih.gov/pubmed/26770398
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