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The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1

Shiga toxin (Stx)-producing Escherichia coli (STEC) infections can lead to life-threatening complications, including hemorrhagic colitis (HC) and hemolytic-uremic syndrome (HUS), which is the most common cause of acute renal failure in children in the United States. Stx1 and Stx2 are AB5 toxins cons...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Basu, Debaleena, Li, Xiao-Ping, Kahn, Jennifer N., May, Kerrie L., Kahn, Peter C., Tumer, Nilgun E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693993/
https://ncbi.nlm.nih.gov/pubmed/26483409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00994-15
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