Do the A Subunits Contribute to the Differences in the Toxicity of Shiga Toxin 1 and Shiga Toxin 2?

Eitemau Tebyg

• The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1
  gan: Basu, Debaleena, et al.
  Cyhoeddwyd: (2015)
• Conserved Arginines at the P-Protein Stalk Binding Site and the Active Site Are Critical for Ribosome Interactions of Shiga Toxins but Do Not Contribute to Differences in the Affinity of the A1 Subunits for the Ribosome
  gan: Basu, Debaleena, et al.
  Cyhoeddwyd: (2016)
• Shiga toxin 1 is more dependent on the P proteins of the ribosomal stalk for depurination activity than Shiga toxin 2
  gan: Chiou, Jia-Chi, et al.
  Cyhoeddwyd: (2011)
• Interaction of Ricin and Shiga Toxins with Ribosomes
  gan: Tumer, Nilgun E., et al.
  Cyhoeddwyd: (2012)
• Identification of amino acids critical for the cytotoxicity of Shiga toxins 1 and 2 in Saccharomyces cerevisiae
  gan: Di, Rong, et al.
  Cyhoeddwyd: (2010)