Expression of activation‐induced cytidine deaminase enhances the clearance of pneumococcal pneumonia: evidence of a subpopulation of protective anti‐pneumococcal B1a cells

We describe a protective early acquired immune response to pneumococcal pneumonia that is mediated by a subset of B1a cells. Mice deficient in B1 cells (xid), or activation‐induced cytidine deaminase (AID (−/−)), or invariant natural killer T (iNKT) cells (Jα18 (−/−)), or interleukin‐13 (IL‐13 (−/−)...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Yamamoto, Natsuo, Kerfoot, Steven M., Hutchinson, Andrew T., Dela Cruz, Charles S., Nakazawa, Naomi, Szczepanik, Marian, Majewska‐Szczepanik, Monika, Nazimek, Katarzyna, Ohana, Noboru, Bryniarski, Krzysztof, Mori, Tsutomu, Muramatsu, Masamichi, Kanemitsu, Keiji, Askenase, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693878/
https://ncbi.nlm.nih.gov/pubmed/26456931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12544
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