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Identification of potential glucocorticoid receptor therapeutic targets in multiple myeloma

Glucocorticoids (GC) are a cornerstone of combination therapies for multiple myeloma. However, patients ultimately develop resistance to GCs frequently based on decreased glucocorticoid receptor (GR) expression. An understanding of the direct targets of GC actions, which induce cell death, is expect...

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Détails bibliographiques
Publié dans:Nucl Recept Signal
Auteurs principaux: Thomas, Alexandra L., Coarfa, Cristian, Qian, Jun, Wilkerson, Joseph J., Rajapakshe, Kimal, Krett, Nancy L., Gunaratne, Preethi H., Rosen, Steven T.
Format: Artigo
Langue:Inglês
Publié: Nuclear Receptor Signaling Atlas 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693629/
https://ncbi.nlm.nih.gov/pubmed/26715915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1621/nrs.13006
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