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Dual regulation of glucocorticoid-induced leucine zipper (GILZ) by the glucocorticoid receptor and the PI3-kinase/AKT pathways in multiple myeloma

Glucocorticoids (GCs) are effective therapeutics commonly used in multiple myeloma (MM) treatment. Clarifying the pathway of GC-induced apoptosis is crucial to understanding the process of drug resistance and to the development of new targets for MM treatment. We have previously published results of...

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Hlavní autoři: Grugan, Katharine D., Ma, Chunguang, Singhal, Seema, Krett, Nancy L., Rosen, Steven T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725965/
https://ncbi.nlm.nih.gov/pubmed/18499442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2007.11.003
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