Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a fatal plasma cell malignancy exhibiting enhanced glucose consumption associated with an aerobic glycolytic phenotype (i.e., the Warburg effect). We have previously demonstrated that myeloma cells exhibit constitutive plasma membrane (PM) localization of GLUT4,...

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Autors principals: Cheng, Javelin C, McBrayer, Samuel K, Coarfa, Cristian, Dalva-Aydemir, Sevim, Gunaratne, Preethi H, Carpten, John D, Keats, Jonathan K, Rosen, Steven T, Shanmugam, Mala
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Rapid Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178207/
https://ncbi.nlm.nih.gov/pubmed/24280290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-14
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