Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a fatal plasma cell malignancy exhibiting enhanced glucose consumption associated with an aerobic glycolytic phenotype (i.e., the Warburg effect). We have previously demonstrated that myeloma cells exhibit constitutive plasma membrane (PM) localization of GLUT4,...

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Detalhes bibliográficos
Main Authors: Cheng, Javelin C, McBrayer, Samuel K, Coarfa, Cristian, Dalva-Aydemir, Sevim, Gunaratne, Preethi H, Carpten, John D, Keats, Jonathan K, Rosen, Steven T, Shanmugam, Mala
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178207/
https://ncbi.nlm.nih.gov/pubmed/24280290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-1-14
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