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Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme

BACKGROUND: Cycling hypoxia is a well-recognized phenomenon within animal and human solid tumors. It contributes to the resistance to cytotoxic therapies through anti-apoptotic effects. However, the mechanism underlying cycling hypoxia-mediated anti-apoptosis remains unclear. METHODS: Reactive oxyge...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Chen, Wei-Ling, Wang, Chi-Chung, Lin, Yu-Jung, Wu, Chung-Pu, Hsieh, Chia-Hung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693410/
https://ncbi.nlm.nih.gov/pubmed/26711814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0758-8
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