NADPH Oxidase Subunit 4-Mediated Reactive Oxygen Species Contribute to Cycling Hypoxia-Promoted Tumor Progression in Glioblastoma Multiforme

BACKGROUND: Cycling and chronic tumor hypoxia are involved in tumor development and growth. However, the impact of cycling hypoxia and its molecular mechanism on glioblastoma multiforme (GBM) progression remain unclear. METHODOLOGY: Glioblastoma cell lines, GBM8401 and U87, and their xenografts were...

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Detalhes bibliográficos
Main Authors: Hsieh, Chia-Hung, Shyu, Woei-Cherng, Chiang, Chien-Yi, Kuo, Jung-Wen, Shen, Wu-Chung, Liu, Ren-Shyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174133/
https://ncbi.nlm.nih.gov/pubmed/21935366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023945
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