New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins

The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA. Inosine can have a profound effect on the RNAs that are edited, not only changing the base-pairing properties, but can also result in recoding, as inosine...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Mannion, Niamh, Arieti, Fabiana, Gallo, Angela, Keegan, Liam P., O’Connell, Mary A.
Format: Artigo
Language:Inglês
Published: MDPI 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693238/
https://ncbi.nlm.nih.gov/pubmed/26437436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5042338
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