The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

RNA editing by deamination of specific adenosine bases to inosines during pre-mRNA processing generates edited isoforms of proteins. Recoding RNA editing is more widespread in Drosophila than in vertebrates. Editing levels rise strongly at metamorphosis, and Adar(5G1) null mutant flies lack editing...

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Bibliografske podrobnosti
Main Authors: Li, Xianghua, Overton, Ian M., Baines, Richard A., Keegan, Liam P., O’Connell, Mary A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902911/
https://ncbi.nlm.nih.gov/pubmed/24137011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt909
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