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An ADAR that edits transcripts encoding ion channel subunits functions as a dimer
In this report, we establish that Drosophila ADAR (adenosine deaminase acting on RNA) forms a dimer on double-stranded (ds) RNA, a process essential for editing activity. The minimum region required for dimerization is the N-terminus and dsRNA-binding domain 1 (dsRBD1). Single point mutations within...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165651/ https://ncbi.nlm.nih.gov/pubmed/12840004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg327 |
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