An ADAR that edits transcripts encoding ion channel subunits functions as a dimer

In this report, we establish that Drosophila ADAR (adenosine deaminase acting on RNA) forms a dimer on double-stranded (ds) RNA, a process essential for editing activity. The minimum region required for dimerization is the N-terminus and dsRNA-binding domain 1 (dsRBD1). Single point mutations within...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	EMBO J
Päätekijät:	Gallo, Angela, Keegan, Liam P., Ring, Gillian M., O’Connell, Mary A.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Publishing Group 2003
Aiheet:	Articles
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12840004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg327
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!