An ADAR that edits transcripts encoding ion channel subunits functions as a dimer

In this report, we establish that Drosophila ADAR (adenosine deaminase acting on RNA) forms a dimer on double-stranded (ds) RNA, a process essential for editing activity. The minimum region required for dimerization is the N-terminus and dsRNA-binding domain 1 (dsRBD1). Single point mutations within...

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Pubblicato in:	EMBO J
Autori principali:	Gallo, Angela, Keegan, Liam P., Ring, Gillian M., O’Connell, Mary A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165651/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12840004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg327
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