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Arsenic Disruption of DNA Damage Responses—Potential Role in Carcinogenesis and Chemotherapy
Arsenic is a Class I human carcinogen and is widespread in the environment. Chronic arsenic exposure causes cancer in skin, lung and bladder, as well as in other organs. Paradoxically, arsenic also is a potent chemotherapeutic against acute promyelocytic leukemia and can potentiate the cytotoxic eff...
Guardat en:
| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693233/ https://ncbi.nlm.nih.gov/pubmed/26404387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5042184 |
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