Sodium Arsenite ± Hyperthermia Sensitizes p53-Expressing Human Ovarian Cancer Cells to Cisplatin by Modulating Platinum-DNA Damage Responses

Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer death in the United States. Cisplatin is a DNA damaging agent initially effective against EOC but limited by resistance. P53 plays a critical role in cellular response to DNA damage and has been implicated in EOC response t...

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Detalhes bibliográficos
Main Authors: Muenyi, Clarisse S., Pinhas, Allan R., Fan, Teresa W., Brock, Guy N., Helm, C. William, States, J. Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genetic Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327868/
https://ncbi.nlm.nih.gov/pubmed/22331493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs085
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