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Arsenic Disruption of DNA Damage Responses—Potential Role in Carcinogenesis and Chemotherapy

Arsenic is a Class I human carcinogen and is widespread in the environment. Chronic arsenic exposure causes cancer in skin, lung and bladder, as well as in other organs. Paradoxically, arsenic also is a potent chemotherapeutic against acute promyelocytic leukemia and can potentiate the cytotoxic eff...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Muenyi, Clarisse S., Ljungman, Mats, States, J. Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693233/
https://ncbi.nlm.nih.gov/pubmed/26404387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5042184
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