Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms

Although targeted therapies are initially effective, resistance inevitably emerges. Several methods, such as genetic analysis of resistant clinical specimens, have been applied to uncover these resistance mechanisms to facilitate follow-up care. Although these approaches have led to clinically relev...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Korpal, Manav, Feala, Jacob, Puyang, Xiaoling, Zou, Jian, Ramos, Alex H., Wu, Jeremy, Baumeister, Timm, Yu, Lihua, Warmuth, Markus, Zhu, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2015
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692793/
https://ncbi.nlm.nih.gov/pubmed/26710000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52879
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