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Uncover disease genes by maximizing information flow in the phenome–interactome network

Motivation: Pinpointing genes that underlie human inherited diseases among candidate genes in susceptibility genetic regions is the primary step towards the understanding of pathogenesis of diseases. Although several probabilistic models have been proposed to prioritize candidate genes using phenoty...

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Autors principals: Chen, Yong, Jiang, Tao, Jiang, Rui
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117332/
https://ncbi.nlm.nih.gov/pubmed/21685067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr213
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