A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1.
Ribozymes have enormous potential as antiviral agents. We have previously reported that a hairpin ribozyme expressed under the control of the beta-actin promoter that cleaves human immunodeficiency virus type 1 (HIV-1) RNA in the leader sequence can inhibit HIV-1 (pHXB2gpt) expression. For such a ri...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6340 |
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