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Dual modes of membrane binding direct pore formation by Streptolysin O

Effector translocation is central to the virulence of many bacterial pathogens, including Streptococcus pyogenes, which utilizes the cholesterol-dependent cytolysin Streptolysin O (SLO) to translocate the NAD(+) glycohydrolase SPN into host cells during infection. SLO’s translocation activity does n...

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Foilsithe in:Mol Microbiol
Main Authors: Mozola, Cara C., Caparon, Michael G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692278/
https://ncbi.nlm.nih.gov/pubmed/26059530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13085
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