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A novel cholesterol-insensitive mode of membrane binding promotes cytolysin-mediated translocation by Streptolysin O

Cytolysin-mediated translocation (CMT), performed by Streptococcus pyogenes, utilizes the cholesterol-dependent cytolysin Streptolysin O (SLO) to translocate the NAD(+)-glycohydrolase (SPN) into the host cell during infection. SLO is required for CMT and can accomplish this activity without pore for...

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Main Authors: Mozola, Cara C., Magassa, N'Goundo, Caparon, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213296/
https://ncbi.nlm.nih.gov/pubmed/25196983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12786
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