Use of a monoclonal antibody to determine the mode of transmembrane pore formation by streptolysin O.

Murine monoclonal antibodies were generated against streptolysin O. One out of 10 tested immunoglobulin clones exhibited strong neutralizing activity; in solution, the presence of approximately two to four antibody molecules per toxin monomer effected 50% neutralization of hemolytic toxin activity....

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hugo, F, Reichwein, J, Arvand, M, Krämer, S, Bhakdi, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260217/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3781620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.54.3.641-645.1986
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