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Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate
RAS GTPase is a prototype for nucleotide-binding proteins that function by cycling between GTP and GDP, with hydrogen atoms playing an important role in the GTP hydrolysis mechanism. It is one of the most well studied proteins in the superfamily of small GTPases, which has representatives in a wide...
में बचाया:
में प्रकाशित: | J Biol Chem |
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मुख्य लेखकों: | , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692228/ https://ncbi.nlm.nih.gov/pubmed/26515069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.679860 |
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