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Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

The crystal structure of a ternary complex of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) heterodimer (p66/p51), a 19-base/18-base double-stranded DNA template-primer, and a monoclonal antibody Fab fragment has been determined at 3.0 A resolution. The four individual subdoma...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Jacobo-Molina, A, Ding, J, Nanni, R G, Clark, A D, Lu, X, Tantillo, C, Williams, R L, Kamer, G, Ferris, A L, Clark, P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687065/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6320
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