Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase.

Using BspMI cassette vectors, we have constructed a series of mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that cause specific amino acid substitutions within the polymerase domain. The RNA-dependent DNA polymerase, DNA-dependent DNA polymerase, and RNase H act...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Boyer, P L, Ferris, A L, Hughes, S H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240464/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1279205/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.12.7533-7537.1992
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