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Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase.

Using BspMI cassette vectors, we have constructed a series of mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that cause specific amino acid substitutions within the polymerase domain. The RNA-dependent DNA polymerase, DNA-dependent DNA polymerase, and RNase H act...

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Bibliografiske detaljer
Main Authors: Boyer, P L, Ferris, A L, Hughes, S H
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC240464/
https://ncbi.nlm.nih.gov/pubmed/1279205
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